1sc7
From Proteopedia
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| - | {{Seed}} | ||
[[Image:1sc7.png|left|200px]] | [[Image:1sc7.png|left|200px]] | ||
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{{ABSTRACT_PUBMED_15801827}} | {{ABSTRACT_PUBMED_15801827}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: DNA topoisomerase I, camptothecin-resistant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=126420 126420]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1sc7]] is a 4 chain structure of [[Topoisomerase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SC7 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Topoisomerase]] | ||
==Reference== | ==Reference== | ||
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[[Category: Poison]] | [[Category: Poison]] | ||
[[Category: Topoisomerase i]] | [[Category: Topoisomerase i]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:30:28 2009'' | ||
Revision as of 02:35, 27 December 2010
Contents |
Human DNA Topoisomerase I (70 Kda) In Complex With The Indenoisoquinoline MJ-II-38 and Covalent Complex With A 22 Base Pair DNA Duplex
Template:ABSTRACT PUBMED 15801827
About this Structure
1sc7 is a 4 chain structure of Topoisomerase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Staker BL, Feese MD, Cushman M, Pommier Y, Zembower D, Stewart L, Burgin AB. Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex. J Med Chem. 2005 Apr 7;48(7):2336-45. PMID:15801827 doi:10.1021/jm049146p
Categories: DNA topoisomerase | Homo sapiens | Burgin, A B. | Cushman, M. | Feese, M D. | Pommier, Y. | Staker, B L. | Stewart, L. | Zembower, D. | Dna | Drug | Idenoisoquinoline | Poison | Topoisomerase i
