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1sc7

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{{Seed}}
 
[[Image:1sc7.png|left|200px]]
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{{ABSTRACT_PUBMED_15801827}}
{{ABSTRACT_PUBMED_15801827}}
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==Disease==
 
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Known disease associated with this structure: DNA topoisomerase I, camptothecin-resistant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=126420 126420]]
 
==About this Structure==
==About this Structure==
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1SC7 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SC7 OCA].
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[[1sc7]] is a 4 chain structure of [[Topoisomerase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SC7 OCA].
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==See Also==
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*[[Topoisomerase]]
==Reference==
==Reference==
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[[Category: Poison]]
[[Category: Poison]]
[[Category: Topoisomerase i]]
[[Category: Topoisomerase i]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:30:28 2009''
 

Revision as of 02:35, 27 December 2010

Image:1sc7.png

Template:STRUCTURE 1sc7

Contents

Human DNA Topoisomerase I (70 Kda) In Complex With The Indenoisoquinoline MJ-II-38 and Covalent Complex With A 22 Base Pair DNA Duplex

Template:ABSTRACT PUBMED 15801827

About this Structure

1sc7 is a 4 chain structure of Topoisomerase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Staker BL, Feese MD, Cushman M, Pommier Y, Zembower D, Stewart L, Burgin AB. Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex. J Med Chem. 2005 Apr 7;48(7):2336-45. PMID:15801827 doi:10.1021/jm049146p

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