3heg

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Revision as of 12:23, 28 December 2010

Template:STRUCTURE 3heg

P38 in complex with Sorafenib

Template:ABSTRACT PUBMED 20337484

About this Structure

3heg is a 1 chain structure of [[]] with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Namboodiri HV, Bukhtiyarova M, Ramcharan J, Karpusas M, Lee Y, Springman EB. Analysis of imatinib and sorafenib binding to p38alpha compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG-out form of protein kinases. Biochemistry. 2010 May 4;49(17):3611-8. PMID:20337484 doi:10.1021/bi100070r

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OCA

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