2hg4

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Revision as of 13:15, 28 December 2010

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Template:STRUCTURE 2hg4

Contents 1 Structure of the ketosynthase-acyltransferase didomain of module 5 from DEBS. 2 About this Structure 3 See Also 4 Reference

Structure of the ketosynthase-acyltransferase didomain of module 5 from DEBS.

Template:ABSTRACT PUBMED 16844787

About this Structure

2hg4 is a 6 chain structure with sequence from Saccharopolyspora erythraea. Full crystallographic information is available from OCA.

See Also

• 6-deoxyerythronolide B synthase (DEBS)

Reference

• Tang Y, Kim CY, Mathews II, Cane DE, Khosla C. The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase. Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11124-9. Epub 2006 Jul 14. PMID:16844787
• Kim CY, Alekseyev VY, Chen AY, Tang Y, Cane DE, Khosla C. Reconstituting modular activity from separated domains of 6-deoxyerythronolide B synthase. Biochemistry. 2004 Nov 9;43(44):13892-8. PMID:15518537 doi:10.1021/bi048418n
• Cane DE, Walsh CT, Khosla C. Harnessing the biosynthetic code: combinations, permutations, and mutations. Science. 1998 Oct 2;282(5386):63-8. PMID:9756477