3nzs

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'''Unreleased structure'''
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[[Image:3nzs.jpg|left|200px]]
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The entry 3nzs is ON HOLD until Paper Publication
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{{STRUCTURE_3nzs| PDB=3nzs | SCENE= }}
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Authors: Murray, J.M., Wiesmann, C.
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===Structure-based Optimization of Pyrazolo -Pyrimidine and -Pyridine Inhibitors of PI3-Kinase===
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Description: Structure-based Optimization of Pyrazolo -Pyrimidine and -Pyridine Inhibitors of PI3-Kinase
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 09:33:37 2010''
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{{ABSTRACT_PUBMED_20822905}}
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==About this Structure==
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[[3nzs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NZS OCA].
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==Reference==
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<ref group="xtra">PMID:20822905</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
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[[Category: Murray, J M.]]
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[[Category: Wiesmann, C.]]
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[[Category: Kinase p110]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 18:37, 29 December 2010

Image:3nzs.jpg

Template:STRUCTURE 3nzs

Structure-based Optimization of Pyrazolo -Pyrimidine and -Pyridine Inhibitors of PI3-Kinase

Template:ABSTRACT PUBMED 20822905

About this Structure

3nzs is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Staben ST, Heffron TP, Sutherlin DP, Bhat SR, Castanedo GM, Chuckowree IS, Dotson J, Folkes AJ, Friedman LS, Lee L, Lesnick J, Lewis C, Murray JM, Nonomiya J, Olivero AG, Plise E, Pang J, Prior WW, Salphati L, Rouge L, Sampath D, Tsui V, Wan NC, Wang S, Weismann C, Wu P, Zhu BY. Structure-based optimization of pyrazolo-pyrimidine and -pyridine inhibitors of PI3-kinase. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6048-51. Epub 2010 Aug 19. PMID:20822905 doi:10.1016/j.bmcl.2010.08.067

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