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3pjc
From Proteopedia
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| + | {{STRUCTURE_3pjc| PDB=3pjc | SCENE= }} | ||
| - | + | ===Crystal structure of JAK3 complexed with a potent ATP site inhibitor showing high selectivity within the Janus kinase family=== | |
| - | Description: Crystal structure of JAK3 complexed with a potent ATP site inhibitor showing high selectivity within the Janus kinase family | ||
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_21155605}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 21155605 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_21155605}} | ||
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| + | ==About this Structure== | ||
| + | [[3pjc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PJC OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:21155605</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Non-specific protein-tyrosine kinase]] | ||
| + | [[Category: Kroemer, M.]] | ||
| + | [[Category: Tavares, G A.]] | ||
| + | [[Category: Thoma, G.]] | ||
| + | [[Category: Zerwes, H G.]] | ||
| + | [[Category: Atp site kinase inhibitor]] | ||
| + | [[Category: Atp-binding]] | ||
| + | [[Category: Small molecule inhibitor]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 18:40, 29 December 2010
Crystal structure of JAK3 complexed with a potent ATP site inhibitor showing high selectivity within the Janus kinase family
Template:ABSTRACT PUBMED 21155605
About this Structure
3pjc is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Thoma G, Nuninger F, Falchetto R, Hermes E, Tavares GA, Vangrevelinghe E, Zerwes HG. Identification of a Potent Janus Kinase 3 Inhibitor with High Selectivity within the Janus Kinase Family. J Med Chem. 2010 Dec 14. PMID:21155605 doi:10.1021/jm101157q
