3lhg

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==About this Structure==
==About this Structure==
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3LHG is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LHG OCA].
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[[3lhg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LHG OCA].
==Reference==
==Reference==
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[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Inhibitor]]
[[Category: Inhibitor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 21 10:14:46 2010''
 

Revision as of 03:21, 2 January 2011

Template:STRUCTURE 3lhg

Bace1 in complex with the aminohydantoin Compound 4g

Template:ABSTRACT PUBMED 20202842

About this Structure

3lhg is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Zhou P, Li Y, Fan Y, Wang Z, Chopra R, Olland A, Hu Y, Magolda RL, Pangalos M, Reinhart PH, Turner MJ, Bard J, Malamas MS, Robichaud AJ. Pyridinyl aminohydantoins as small molecule BACE1 inhibitors. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2326-9. Epub 2010 Feb 12. PMID:20202842 doi:10.1016/j.bmcl.2010.01.136

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