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3lhg

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Revision as of 03:21, 2 January 2011

Image:3lhg.png

Template:STRUCTURE 3lhg

Bace1 in complex with the aminohydantoin Compound 4g

Template:ABSTRACT PUBMED 20202842

About this Structure

3lhg is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Zhou P, Li Y, Fan Y, Wang Z, Chopra R, Olland A, Hu Y, Magolda RL, Pangalos M, Reinhart PH, Turner MJ, Bard J, Malamas MS, Robichaud AJ. Pyridinyl aminohydantoins as small molecule BACE1 inhibitors. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2326-9. Epub 2010 Feb 12. PMID:20202842 doi:10.1016/j.bmcl.2010.01.136

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OCA

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