2ogz

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Revision as of 11:57, 3 January 2011

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Template:STRUCTURE 2ogz

Contents 1 Crystal structure of DPP-IV complexed with Lilly aryl ketone inhibitor 2 About this Structure 3 See Also 4 Reference

Crystal structure of DPP-IV complexed with Lilly aryl ketone inhibitor

Template:ABSTRACT PUBMED 17239592

About this Structure

2ogz is a 2 chain structure of Dipeptidyl peptidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Dipeptidyl peptidase

Reference

• Sheehan SM, Mest HJ, Watson BM, Klimkowski VJ, Timm DE, Cauvin A, Parsons SH, Shi Q, Canada EJ, Wiley MR, Ruehter G, Evers B, Petersen S, Blaszczak LC, Pulley SR, Margolis BJ, Wishart GN, Renson B, Hankotius D, Mohr M, Zechel JC, Michael Kalbfleisch J, Dingess-Hammond EA, Boelke A, Weichert AG. Discovery of non-covalent dipeptidyl peptidase IV inhibitors which induce a conformational change in the active site. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1765-8. Epub 2006 Dec 24. PMID:17239592 doi:10.1016/j.bmcl.2006.12.074