2z4w

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m (Protected "2z4w" [edit=sysop:move=sysop])
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[[Category: Oldfield, E.]]
[[Category: Oldfield, E.]]
[[Category: Wang, A H.J.]]
[[Category: Wang, A H.J.]]
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[[Category: Bisphosphonate]]
 
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[[Category: Geranylgeranyl pyrophosphate]]
 
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[[Category: Prenyltransferase]]
 
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[[Category: Transferase]]
 
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[[Category: Transferase-transferase inhibitor complex]]
 

Revision as of 15:41, 5 January 2011

Template:STRUCTURE 2z4w

S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-749

Template:ABSTRACT PUBMED 18800762

About this Structure

2z4w is a 2 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  • K-M Chen C, Hudock MP, Zhang Y, Guo RT, Cao R, No JH, Liang PH, Ko TP, Chang TH, Chang SC, Song Y, Axelson J, Kumar A, Wang AH, Oldfield E. Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation. J Med Chem. 2008 Sep 25;51(18):5594-607. PMID:18800762 doi:10.1021/jm800325y

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