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3okh
From Proteopedia
(Difference between revisions)
m (Protected "3okh" [edit=sysop:move=sysop]) |
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Rudolph, M G.]] | [[Category: Rudolph, M G.]] | ||
| - | [[Category: Bile acid]] | ||
| - | [[Category: Cholesterol]] | ||
| - | [[Category: Coactivator]] | ||
| - | [[Category: Dna-binding]] | ||
| - | [[Category: Fxr alternative splicing]] | ||
| - | [[Category: Hormone receptor]] | ||
| - | [[Category: Ligand binding domain transcription regulation]] | ||
| - | [[Category: Nuclear receptor]] | ||
| - | [[Category: Nucleus]] | ||
| - | [[Category: Receptor]] | ||
| - | [[Category: Transcription]] | ||
Revision as of 04:36, 12 January 2011
Crystal structure of human FXR in complex with 2-(4-chlorophenyl)-1-[(1S)-1-cyclohexyl-2-(cyclohexylamino)-2-oxoethyl]-1H-benzimidazole-6-carboxylic acid
Template:ABSTRACT PUBMED 21134747
About this Structure
3okh is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Richter HG, Benson GM, Blum D, Chaput E, Feng S, Gardes C, Grether U, Hartman P, Kuhn B, Martin RE, Plancher JM, Rudolph MG, Schuler F, Taylor S, Bleicher KH. Discovery of novel and orally active FXR agonists for the potential treatment of dyslipidemia & diabetes. Bioorg Med Chem Lett. 2011 Jan 1;21(1):191-4. Epub 2010 Nov 12. PMID:21134747 doi:10.1016/j.bmcl.2010.11.039
