3klh
From Proteopedia
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===Crystal structure of AZT-Resistant HIV-1 Reverse Transcriptase crosslinked to post-translocation AZTMP-Terminated DNA (COMPLEX P)=== | ===Crystal structure of AZT-Resistant HIV-1 Reverse Transcriptase crosslinked to post-translocation AZTMP-Terminated DNA (COMPLEX P)=== | ||
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_20852643}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 20852643 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_20852643}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3klh]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLH OCA]. | |
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:20852643</ref><references group="xtra"/> | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
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[[Category: Sarafianos, S G.]] | [[Category: Sarafianos, S G.]] | ||
[[Category: Tu, X.]] | [[Category: Tu, X.]] | ||
| - | [[Category: Aid]] | ||
| - | [[Category: Azt]] | ||
| - | [[Category: Azt excision]] | ||
| - | [[Category: Azt resistance]] | ||
| - | [[Category: Azt resistance mutation]] | ||
| - | [[Category: Dna polymerase]] | ||
| - | [[Category: Dna-directed dna polymerase]] | ||
| - | [[Category: Hiv]] | ||
| - | [[Category: Hiv-1]] | ||
| - | [[Category: Magnesium]] | ||
| - | [[Category: Metal-binding]] | ||
| - | [[Category: Multifunctional enzyme]] | ||
| - | [[Category: Nrti]] | ||
| - | [[Category: Nuclease]] | ||
| - | [[Category: Nucleoside inhibitor]] | ||
| - | [[Category: Nucleotide excision]] | ||
| - | [[Category: P51/p66]] | ||
| - | [[Category: Resistance mechanism]] | ||
| - | [[Category: Reverse transcriptase]] | ||
| - | [[Category: Rna-directed dna polymerase]] | ||
| - | [[Category: Rt]] | ||
| - | [[Category: Transferase]] | ||
| - | [[Category: Transferase-dna complex]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 14:44:39 2010'' | ||
Revision as of 04:36, 12 January 2011
Crystal structure of AZT-Resistant HIV-1 Reverse Transcriptase crosslinked to post-translocation AZTMP-Terminated DNA (COMPLEX P)
Template:ABSTRACT PUBMED 20852643
About this Structure
3klh is a 6 chain structure with sequence from Human immunodeficiency virus 1 and Mus musculus. Full crystallographic information is available from OCA.
Reference
- Tu X, Das K, Han Q, Bauman JD, Clark AD Jr, Hou X, Frenkel YV, Gaffney BL, Jones RA, Boyer PL, Hughes SH, Sarafianos SG, Arnold E. Structural basis of HIV-1 resistance to AZT by excision. Nat Struct Mol Biol. 2010 Oct;17(10):1202-9. Epub 2010 Sep 19. PMID:20852643 doi:10.1038/nsmb.1908
