3kle

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===Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA===
===Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA===
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{{ABSTRACT_PUBMED_20852643}}
==About this Structure==
==About this Structure==
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==See Also==
==See Also==
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*[[AZT-resistant HIV-1 reverse transcriptase]]
*[[Phl p 2]]
*[[Phl p 2]]
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==Reference==
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<ref group="xtra">PMID:20852643</ref><references group="xtra"/>
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Arnold, E.]]
[[Category: Arnold, E.]]
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[[Category: Sarafianos, S G.]]
[[Category: Sarafianos, S G.]]
[[Category: Tu, X.]]
[[Category: Tu, X.]]
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[[Category: Aid]]
 
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[[Category: Azt]]
 
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[[Category: Azt adenosine dinucleoside tetraphosphate]]
 
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[[Category: Azt resistance mechanism]]
 
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[[Category: Aztp4a]]
 
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[[Category: Aztppppa]]
 
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[[Category: Dna polymerase]]
 
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[[Category: Dna-directed dna polymerase]]
 
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[[Category: Endonuclease]]
 
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[[Category: Hiv]]
 
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[[Category: Hiv-1]]
 
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[[Category: Hydrolase]]
 
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[[Category: Magnesium]]
 
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[[Category: Metal-binding]]
 
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[[Category: Multifunctional enzyme]]
 
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[[Category: Myristate]]
 
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[[Category: Nrti]]
 
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[[Category: Nrti resistance]]
 
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[[Category: Nuclease]]
 
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[[Category: Nucleoside inhibitor]]
 
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[[Category: Nucleotide excision]]
 
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[[Category: P51/p66]]
 
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[[Category: Resistance mutation]]
 
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[[Category: Reverse transcriptase]]
 
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[[Category: Rna-directed dna polymerase]]
 
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[[Category: Rt]]
 
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[[Category: Thymidine analog mutation]]
 
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[[Category: Transferase]]
 
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[[Category: Transferase-dna complex]]
 

Revision as of 04:38, 12 January 2011

Template:STRUCTURE 3kle

Contents

Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA

Template:ABSTRACT PUBMED 20852643

About this Structure

3kle is a 16 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

Reference

  • Tu X, Das K, Han Q, Bauman JD, Clark AD Jr, Hou X, Frenkel YV, Gaffney BL, Jones RA, Boyer PL, Hughes SH, Sarafianos SG, Arnold E. Structural basis of HIV-1 resistance to AZT by excision. Nat Struct Mol Biol. 2010 Oct;17(10):1202-9. Epub 2010 Sep 19. PMID:20852643 doi:10.1038/nsmb.1908

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OCA

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