We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
3n84
From Proteopedia
(Difference between revisions)
m (Protected "3n84" [edit=sysop:move=sysop]) |
Revision as of 05:14, 12 January 2011
Crystal Structure of the Grb2 SH2 Domain in Complex with a 23-Membered Macrocyclic Ligand Having the Sequence pYVNVP
Template:ABSTRACT PUBMED 21116482
About this Structure
3n84 is a 12 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Delorbe JE, Clements JH, Whiddon BB, Martin SF. Thermodynamic and Structural Effects of Macrocyclization as a Constraining Method in Protein-Ligand Interactions. ACS Med Chem Lett. 2010 Nov 11;1(8):448-452. PMID:21116482 doi:10.1021/ml100142y
