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2iub
From Proteopedia
(New page: 200px<br /> <applet load="2iub" size="450" color="white" frame="true" align="right" spinBox="true" caption="2iub, resolution 2.90Å" /> '''CRYSTAL STRUCTURE O...) |
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==About this Structure== | ==About this Structure== | ||
| - | 2IUB is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]] with CL and MG as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2IUB OCA]]. | + | 2IUB is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]] with CL and MG as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2IUB OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: membrane protein]] | [[Category: membrane protein]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:29:40 2007'' |
Revision as of 09:24, 30 October 2007
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CRYSTAL STRUCTURE OF A DIVALENT METAL ION TRANSPORTER CORA AT 2.9 A RESOLUTION.
Overview
CorA family members are ubiquitously distributed transporters of divalent, metal cations and are considered to be the primary Mg2+ transporter of, Bacteria and Archaea. We have determined a 2.9 angstrom resolution, structure of CorA from Thermotoga maritima that reveals a pentameric, cone-shaped protein. Two potential regulatory metal binding sites are, found in the N-terminal domain that bind both Mg2+ and Co2+. The structure, of CorA supports an efflux system involving dehydration and rehydration of, divalent metal ions potentially mediated by a ring of conserved aspartate, residues at the cytoplasmic entrance and a carbonyl funnel at the, periplasmic side of the pore.
About this Structure
2IUB is a [Single protein] structure of sequence from [Thermotoga maritima] with CL and MG as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Crystal structure of a divalent metal ion transporter CorA at 2.9 angstrom resolution., Eshaghi S, Niegowski D, Kohl A, Martinez Molina D, Lesley SA, Nordlund P, Science. 2006 Jul 21;313(5785):354-7. PMID:16857941
Page seeded by OCA on Tue Oct 30 11:29:40 2007
