2iuk
From Proteopedia
(New page: 200px<br /> <applet load="2iuk" size="450" color="white" frame="true" align="right" spinBox="true" caption="2iuk, resolution 2.4Å" /> '''CRYSTAL STRUCTURE OF...) |
|||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
| - | 2IUK is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Glycine_max Glycine max]] with FE as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.12 1.13.11.12]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2IUK OCA]]. | + | 2IUK is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Glycine_max Glycine max]] with FE as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/Lipoxygenase Lipoxygenase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.12 1.13.11.12]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2IUK OCA]]. |
==Reference== | ==Reference== | ||
Crystal structures of vegetative soybean lipoxygenase VLX-B and VLX-D, and comparisons with seed isoforms LOX-1 and LOX-3., Youn B, Sellhorn GE, Mirchel RJ, Gaffney BJ, Grimes HD, Kang C, Proteins. 2006 Dec 1;65(4):1008-20. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17022084 17022084] | Crystal structures of vegetative soybean lipoxygenase VLX-B and VLX-D, and comparisons with seed isoforms LOX-1 and LOX-3., Youn B, Sellhorn GE, Mirchel RJ, Gaffney BJ, Grimes HD, Kang C, Proteins. 2006 Dec 1;65(4):1008-20. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17022084 17022084] | ||
[[Category: Glycine max]] | [[Category: Glycine max]] | ||
| + | [[Category: Lipoxygenase]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Gaffney, B.J.]] | [[Category: Gaffney, B.J.]] | ||
| Line 30: | Line 31: | ||
[[Category: soybean lipoxygenase-d]] | [[Category: soybean lipoxygenase-d]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:30:06 2007'' |
Revision as of 09:25, 30 October 2007
|
CRYSTAL STRUCTURE OF SOYBEAN LIPOXYGENASE-D
Overview
The lipoxygenase family of lipid-peroxidizing, nonheme iron dioxygenases, form products that are precursors for diverse physiological processes in, both plants and animals. In soybean (Glycine max), five vegetative, isoforms, VLX-A, VLX-B, VLX-C, VLX-D, VLX-E, and four seed isoforms LOX-1, LOX-2, LOX-3a, LOX-3b have been identified. In this study, we determined, the crystal structures of the substrate-free forms of two major vegetative, isoforms, with distinct enzymatic characteristics, VLX-B and VLX-D. Their, structures are similar to the two seed isoforms, LOX-1 and LOX-3, having, two domains with similar secondary structural elements: a beta-barrel, N-terminal domain containing highly flexible loops and an alpha-helix-rich, C-terminal catalytic domain. Detailed comparison of the ... [(full description)]
About this Structure
2IUK is a [Single protein] structure of sequence from [Glycine max] with FE as [ligand]. Active as [Lipoxygenase], with EC number [1.13.11.12]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Crystal structures of vegetative soybean lipoxygenase VLX-B and VLX-D, and comparisons with seed isoforms LOX-1 and LOX-3., Youn B, Sellhorn GE, Mirchel RJ, Gaffney BJ, Grimes HD, Kang C, Proteins. 2006 Dec 1;65(4):1008-20. PMID:17022084
Page seeded by OCA on Tue Oct 30 11:30:06 2007
