3o8a
From Proteopedia
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===Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with novel Inhibitor Genz667348=== | ===Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with novel Inhibitor Genz667348=== | ||
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_20702404}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 20702404 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_20702404}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3o8a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O8A OCA]. | |
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:20702404</ref><references group="xtra"/> | ||
[[Category: Dihydroorotate dehydrogenase]] | [[Category: Dihydroorotate dehydrogenase]] | ||
[[Category: Plasmodium falciparum]] | [[Category: Plasmodium falciparum]] | ||
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[[Category: Deng, X.]] | [[Category: Deng, X.]] | ||
[[Category: Phillips, M A.]] | [[Category: Phillips, M A.]] | ||
| - | [[Category: Alpha beta fold]] | ||
| - | [[Category: Dihydroorotate dehydrogenase]] | ||
| - | [[Category: Fad]] | ||
| - | [[Category: Flavoprotein]] | ||
| - | [[Category: Genz667348]] | ||
| - | [[Category: Mitochondrion inner membrane]] | ||
| - | [[Category: Oxidoreductase]] | ||
| - | [[Category: Pyrimidine biosynthesis]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 18 11:51:23 2010'' | ||
Revision as of 05:27, 12 January 2011
Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with novel Inhibitor Genz667348
Template:ABSTRACT PUBMED 20702404
About this Structure
3o8a is a 1 chain structure with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.
Reference
- Booker ML, Bastos CM, Kramer ML, Barker RH Jr, Skerlj R, Sidhu AB, Deng X, Celatka C, Cortese JF, Guerrero Bravo JE, Crespo Llado KN, Serrano AE, Angulo-Barturen I, Jimenez-Diaz MB, Viera S, Garuti H, Wittlin S, Papastogiannidis P, Lin JW, Janse CJ, Khan SM, Duraisingh M, Coleman B, Goldsmith EJ, Phillips MA, Munoz B, Wirth DF, Klinger JD, Wiegand R, Sybertz E. Novel inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with anti-malarial activity in the mouse model. J Biol Chem. 2010 Oct 22;285(43):33054-64. Epub 2010 Aug 11. PMID:20702404 doi:10.1074/jbc.M110.162081
