3nlu

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'''Unreleased structure'''
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[[Image:3nlu.jpg|left|200px]]
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The entry 3nlu is ON HOLD until Paper Publication
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{{STRUCTURE_3nlu| PDB=3nlu | SCENE= }}
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Authors: Xue, F., Li, H., Fang, J., Delker, S.L., Poulos, T.L., Silverman, R.B.
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===Structure of endothelial nitric oxide synthase heme domain complexed with N1-{(3'R,4'R)-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride===
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Description: Structure of endothelial nitric oxide synthase heme domain complexed with N1-{(3'R,4'R)-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 14 16:07:46 2010''
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{{ABSTRACT_PUBMED_20843082}}
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==About this Structure==
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[[3nlu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NLU OCA].
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==Reference==
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<ref group="xtra">PMID:20843082</ref><references group="xtra"/>
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[[Category: Bos taurus]]
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[[Category: Nitric-oxide synthase]]
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[[Category: Delker, S L.]]
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[[Category: Fang, J.]]
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[[Category: Li, H.]]
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[[Category: Poulos, T L.]]
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[[Category: Silverman, R B.]]
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[[Category: Xue, F.]]

Revision as of 06:23, 19 January 2011

Image:3nlu.jpg

Template:STRUCTURE 3nlu

Structure of endothelial nitric oxide synthase heme domain complexed with N1-{(3'R,4'R)-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride

Template:ABSTRACT PUBMED 20843082

About this Structure

3nlu is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Xue F, Li H, Delker SL, Fang J, Martasek P, Roman LJ, Poulos TL, Silverman RB. Potent, highly selective, and orally bioavailable gem-difluorinated monocationic inhibitors of neuronal nitric oxide synthase. J Am Chem Soc. 2010 Oct 13;132(40):14229-38. PMID:20843082 doi:10.1021/ja106175q

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