3nlx

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'''Unreleased structure'''
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[[Image:3nlx.jpg|left|200px]]
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The entry 3nlx is ON HOLD until Paper Publication
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{{STRUCTURE_3nlx| PDB=3nlx | SCENE= }}
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Authors: Li, H., Delker, S.L., Poulos, T.L.
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===Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2- (2,2-Difluoro-2-(3-fluorophenyl)ethylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine===
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Description: Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2-(2,2-Difluoro-2-(3-fluorophenyl)ethylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 14 16:07:48 2010''
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{{ABSTRACT_PUBMED_20843082}}
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==About this Structure==
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[[3nlx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NLX OCA].
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==Reference==
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<ref group="xtra">PMID:20843082</ref><references group="xtra"/>
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[[Category: Nitric-oxide synthase]]
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[[Category: Rattus norvegicus]]
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[[Category: Delker, S L.]]
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[[Category: Li, H.]]
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[[Category: Poulos, T L.]]

Revision as of 06:23, 19 January 2011

Image:3nlx.jpg

Template:STRUCTURE 3nlx

Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2- (2,2-Difluoro-2-(3-fluorophenyl)ethylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine

Template:ABSTRACT PUBMED 20843082

About this Structure

3nlx is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Xue F, Li H, Delker SL, Fang J, Martasek P, Roman LJ, Poulos TL, Silverman RB. Potent, highly selective, and orally bioavailable gem-difluorinated monocationic inhibitors of neuronal nitric oxide synthase. J Am Chem Soc. 2010 Oct 13;132(40):14229-38. PMID:20843082 doi:10.1021/ja106175q

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