2j58

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(New page: 200px<br /> <applet load="2j58" size="450" color="white" frame="true" align="right" spinBox="true" caption="2j58, resolution 2.25&Aring;" /> '''THE STRUCTURE OF WZ...)
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==About this Structure==
==About this Structure==
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2J58 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]] with SO4, OCT and HEX as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2J58 OCA]].
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2J58 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]] with SO4, OCT and HEX as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2J58 OCA]].
==Reference==
==Reference==
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[[Category: membrane protein]]
[[Category: membrane protein]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 18:04:44 2007''
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:33:29 2007''

Revision as of 09:28, 30 October 2007


2j58, resolution 2.25Å

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THE STRUCTURE OF WZA

Overview

Many types of bacteria produce extracellular polysaccharides (EPSs). Some, are secreted polymers and show only limited association with the cell, surface, whereas others are firmly attached to the cell surface and form a, discrete structural layer, the capsule, which envelopes the cell and, allows the bacteria to evade or counteract the host immune system. EPSs, have critical roles in bacterial colonization of surfaces, such as, epithelia and medical implants; in addition some EPSs have important, industrial and biomedical applications in their own right. Here we, describe the 2.26 A resolution structure of the 340 kDa octamer of Wza, an, integral outer membrane lipoprotein, which is essential for group 1, capsule export in Escherichia coli. The transmembrane region is a novel, ... [(full description)]

About this Structure

2J58 is a [Single protein] structure of sequence from [Escherichia coli] with SO4, OCT and HEX as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].

Reference

Wza the translocon for E. coli capsular polysaccharides defines a new class of membrane protein., Dong C, Beis K, Nesper J, Brunkan-Lamontagne AL, Clarke BR, Whitfield C, Naismith JH, Nature. 2006 Nov 9;444(7116):226-9. Epub 2006 Nov 1. PMID:17086202

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