1yas
From Proteopedia
(New page: 200px<br /> <applet load="1yas" size="450" color="white" frame="true" align="right" spinBox="true" caption="1yas, resolution 1.9Å" /> '''HYDROXYNITRILE LYASE...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1YAS is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Hevea_brasiliensis Hevea brasiliensis]] with SO4 and HIS as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.39 4.1.2.39]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1YAS OCA]]. | + | 1YAS is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Hevea_brasiliensis Hevea brasiliensis]] with SO4 and HIS as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Transfered_to_EC_4.1.2.37 Transfered to EC 4.1.2.37]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.39 4.1.2.39]]. Structure known Active Site: CAT. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1YAS OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: Hevea brasiliensis]] | [[Category: Hevea brasiliensis]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| + | [[Category: Transfered to EC 4.1.2.37]] | ||
[[Category: Kratky, C.]] | [[Category: Kratky, C.]] | ||
[[Category: Wagner, U.G.]] | [[Category: Wagner, U.G.]] | ||
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[[Category: oxynitrilase]] | [[Category: oxynitrilase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:36:22 2007'' |
Revision as of 09:31, 30 October 2007
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HYDROXYNITRILE LYASE COMPLEXED WITH HISTIDINE
Overview
BACKGROUND: Over three thousand species of plants, including important, food crops such as cassava, use cyanogenesis, the liberation of HCN upon, tissue damage, as a defense against predation. Detoxification of, cyanogenic food crops requires disruption of the cyanogenic pathway., Hydroxynitrile lyase is one of the key enzymes in cyanogenesis, catalyzing, the decomposition of an alpha-cyanohydrin to form HCN plus the, corresponding aldehyde or ketone. These enzymes are also of potential, utility for industrial syntheses of optically pure chiral cyanohydrins, being used to catalyze the reverse reaction. We set out to gain insight, into the catalytic mechanism of this important class of enzymes by, determining the three-dimensional structure of hydroxynitrile lyase from, the rubber tree, ... [(full description)]
About this Structure
1YAS is a [Single protein] structure of sequence from [Hevea brasiliensis] with SO4 and HIS as [ligands]. Active as [Transfered to EC 4.1.2.37], with EC number [4.1.2.39]. Structure known Active Site: CAT. Full crystallographic information is available from [OCA].
Reference
Mechanism of cyanogenesis: the crystal structure of hydroxynitrile lyase from Hevea brasiliensis., Wagner UG, Hasslacher M, Griengl H, Schwab H, Kratky C, Structure. 1996 Jul 15;4(7):811-22. PMID:8805565
Page seeded by OCA on Tue Oct 30 11:36:22 2007
