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3pp1

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'''Unreleased structure'''
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[[Image:3pp1.jpg|left|200px]]
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The entry 3pp1 is ON HOLD
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{{STRUCTURE_3pp1| PDB=3pp1 | SCENE= }}
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Authors: Dougan, D.R.
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===Crystal Structure of the Human Mitogen-activated protein kinase kinase 1 (MEK 1) in complex with ligand and MgATP===
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Description: Crystal Structure of the Human Mitogen-activated protein kinase kinase 1 (MEK 1) in complex with ligand and MgATP
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 15 08:24:36 2010''
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{{ABSTRACT_PUBMED_21310613}}
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==About this Structure==
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[[3pp1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PP1 OCA].
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==Reference==
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<ref group="xtra">PMID:21310613</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Mitogen-activated protein kinase kinase]]
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[[Category: Dougan, D R.]]

Revision as of 09:59, 23 February 2011

Image:3pp1.jpg

Template:STRUCTURE 3pp1

Crystal Structure of the Human Mitogen-activated protein kinase kinase 1 (MEK 1) in complex with ligand and MgATP

Template:ABSTRACT PUBMED 21310613

About this Structure

3pp1 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Dong Q, Dougan DR, Gong X, Halkowycz P, Jin B, Kanouni T, O'Connell SM, Scorah N, Shi L, Wallace MB, Zhou F. Discovery of TAK-733, a potent and selective MEK allosteric site inhibitor for the treatment of cancer. Bioorg Med Chem Lett. 2011 Mar 1;21(5):1315-9. Epub 2011 Jan 22. PMID:21310613 doi:10.1016/j.bmcl.2011.01.071

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