Colicin E6
From Proteopedia
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- | Colicin E6 is a type of [[Colicin]], a bacteriocin made by ''E. coli'' which acts against other nearby ''E. coli'' to kill them with its 16s rRNase activity; it digests the 16s ribosomal subunit, ultimately leading to the death of the cell. | + | Colicin E6 is a type of [[Colicin]], a bacteriocin made by ''E. coli'' which acts against other nearby ''E. coli'' to kill them with its [[16s rRNase activity]]; it digests the 16s ribosomal subunit, ultimately leading to the death of the cell. |
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==Synthesis and release== | ==Synthesis and release== | ||
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+ | The ColE6 operon is encoded on a plasmid in the ''E. coli'' cell, and includes the [[Colicin Immunity Protein]], [[ImmE6]]. Once the colicin has been produced, it binds to its immunity protein; this protects the colicinogenic cell from the cytotoxic activity of the colicin. | ||
==Mechanism of uptake== | ==Mechanism of uptake== | ||
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==Killing Activities== | ==Killing Activities== |
Revision as of 14:13, 26 February 2011
Colicin E6 is a type of Colicin, a bacteriocin made by E. coli which acts against other nearby E. coli to kill them with its 16s rRNase activity; it digests the 16s ribosomal subunit, ultimately leading to the death of the cell.
Synthesis and release
The ColE6 operon is encoded on a plasmid in the E. coli cell, and includes the Colicin Immunity Protein, ImmE6. Once the colicin has been produced, it binds to its immunity protein; this protects the colicinogenic cell from the cytotoxic activity of the colicin.