Im2
From Proteopedia
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Im2 is the [[Colicin Immunity Protein]] for [[Colicin E2]], produced by the cell at the same time to protect itself from the [[DNase Activity]] of the cytotoxic domain of ColE2. It is released when the [[Colicin]] binds to a cell surface receptor of a target cell. | Im2 is the [[Colicin Immunity Protein]] for [[Colicin E2]], produced by the cell at the same time to protect itself from the [[DNase Activity]] of the cytotoxic domain of ColE2. It is released when the [[Colicin]] binds to a cell surface receptor of a target cell. | ||
| - | Im2 is also capable of binding to [[Colicin E9]], which has a high level of sequence homology to ColE2, and also inhibit the activity of the cytotoxic domain. This structure shows the binding of <scene name='Im2/Cole9frag/1'>colicin E9</scene> to Im2. | + | Im2 is also capable of binding to [[Colicin E9]], which has a high level of sequence homology to ColE2, and also inhibit the activity of the cytotoxic domain. This structure shows the binding of <scene name='Im2/Cole9frag/1'>colicin E9</scene> to <scene name='Im2/Im2/1'>Im2</scene>. |
<Structure load='2wpt' size='500' frame='true' align='right' caption='Im2 bound to ColE9' scene= Im2/Noligands/1 /> | <Structure load='2wpt' size='500' frame='true' align='right' caption='Im2 bound to ColE9' scene= Im2/Noligands/1 /> | ||
Revision as of 20:29, 27 February 2011
Im2 is the Colicin Immunity Protein for Colicin E2, produced by the cell at the same time to protect itself from the DNase Activity of the cytotoxic domain of ColE2. It is released when the Colicin binds to a cell surface receptor of a target cell.
Im2 is also capable of binding to Colicin E9, which has a high level of sequence homology to ColE2, and also inhibit the activity of the cytotoxic domain. This structure shows the binding of to .
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