3ime

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==About this Structure==
==About this Structure==
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3IME is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IME OCA].
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[[3ime]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IME OCA].
==Reference==
==Reference==
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[[Category: Silvestre, H L.]]
[[Category: Silvestre, H L.]]
[[Category: Wen, S.]]
[[Category: Wen, S.]]
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[[Category: Atp-binding]]
 
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[[Category: Cytoplasm]]
 
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[[Category: Drug design]]
 
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[[Category: Enzyme]]
 
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[[Category: Fragment-based]]
 
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[[Category: Ligase]]
 
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[[Category: Magnesium]]
 
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[[Category: Metal-binding]]
 
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[[Category: Mycobacterium tuberculosis]]
 
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[[Category: Nucleotide-binding]]
 
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[[Category: Pantothenate biosynthesis]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 14 10:25:37 2009''
 

Revision as of 06:21, 2 March 2011

Template:STRUCTURE 3ime

Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 2.40 Ang resolution in complex with fragment compound 1-Benzofuran-2-carboxylic acid

About this Structure

3ime is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  • Hung AW, Silvestre HL, Wen S, Ciulli A, Blundell TL, Abell C. Application of fragment growing and fragment linking to the discovery of inhibitors of Mycobacterium tuberculosis pantothenate synthetase. Angew Chem Int Ed Engl. 2009;48(45):8452-6. PMID:19780086 doi:10.1002/anie.200903821

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