3lzb
From Proteopedia
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| - | + | [[Image:3lzb.jpg|left|200px]] | |
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| + | The line below this paragraph, containing "STRUCTURE_3lzb", creates the "Structure Box" on the page. | ||
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| + | {{STRUCTURE_3lzb| PDB=3lzb | SCENE= }} | ||
| - | + | ===EGFR kinase domain complexed with an imidazo[2,1-b]thiazole inhibitor=== | |
| - | Description: EGFR kinase domain complexed with an imidazo[2,1-b]thiazole inhibitor | ||
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_20346655}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 20346655 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_20346655}} | ||
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| + | ==About this Structure== | ||
| + | [[3lzb]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZB OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:20346655</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Receptor protein-tyrosine kinase]] | ||
| + | [[Category: Swinger, K K.]] | ||
Revision as of 06:57, 2 March 2011
EGFR kinase domain complexed with an imidazo[2,1-b]thiazole inhibitor
Template:ABSTRACT PUBMED 20346655
About this Structure
3lzb is a 8 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Fidanze SD, Erickson SA, Wang GT, Mantei R, Clark RF, Sorensen BK, Bamaung NY, Kovar P, Johnson EF, Swinger KK, Stewart KD, Zhang Q, Tucker LA, Pappano WN, Wilsbacher JL, Wang J, Sheppard GS, Bell RL, Davidsen SK, Hubbard RD. Imidazo[2,1-b]thiazoles: multitargeted inhibitors of both the insulin-like growth factor receptor and members of the epidermal growth factor family of receptor tyrosine kinases. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2452-5. Epub 2010 Mar 7. PMID:20346655 doi:10.1016/j.bmcl.2010.03.015
