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Prp24

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'''Prp24''' ('''Pr'''e-mRNA splicing '''P'''rotein 24) is a [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae ''Saccharomyces cerevisiae''] yeast protein that functions in the formation of base pair interactions between the [http://en.wikipedia.org/wiki/U6_spliceosomal_RNA U6] and [http://en.wikipedia.org/wiki/U4_spliceosomal_RNA U4] [http://en.wikipedia.org/wiki/SnRNP snRNPs (small nuclear ribonucleoproteins] to form the U4/U6 di-snRNP in the assembly of the [http://en.wikipedia.org/wiki/Spliceosome spliceosome]. This protein contains four RNA recognition motifs (RRMs) that function in the binding of Prp24 to U6 snRNA. These RRMs domains are conserved in structure and sequence in proteins orthologous to Prp24 in ''Homo sapiens'' and ''Schizosaccharomyces pombe'', as well as in other proteins containing RRMs.
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'''Prp24''' ('''Pr'''e-mRNA splicing '''P'''rotein 24) is a [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae ''Saccharomyces cerevisiae''] yeast protein that functions in the formation of base pair interactions between the [http://en.wikipedia.org/wiki/U6_spliceosomal_RNA U6] and [http://en.wikipedia.org/wiki/U4_spliceosomal_RNA U4] [http://en.wikipedia.org/wiki/SnRNP snRNPs (small nuclear ribonucleoproteins] to form the U4/U6 di-snRNP in the assembly of the [http://en.wikipedia.org/wiki/Spliceosome spliceosome]. This protein is an octamer containing four RNA recognition motifs (RRMs) that function in the binding of Prp24 to U6 snRNA. These RRMs domains are conserved in structure and sequence in proteins orthologous to Prp24 in ''Homo sapiens'' and ''Schizosaccharomyces pombe'', as well as in other proteins containing RRMs.

Revision as of 01:48, 3 March 2011

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Template:STRUCTURE 2ghp

Prp24 (Pre-mRNA splicing Protein 24) is a Saccharomyces cerevisiae yeast protein that functions in the formation of base pair interactions between the U6 and U4 snRNPs (small nuclear ribonucleoproteins to form the U4/U6 di-snRNP in the assembly of the spliceosome. This protein is an octamer containing four RNA recognition motifs (RRMs) that function in the binding of Prp24 to U6 snRNA. These RRMs domains are conserved in structure and sequence in proteins orthologous to Prp24 in Homo sapiens and Schizosaccharomyces pombe, as well as in other proteins containing RRMs.


Contents

Introduction

Functional Role

Structure

References

Proteopedia Page Contributors and Editors (what is this?)

Kara Perdue, Michal Harel, Alexander Berchansky, OCA

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