Ciprofloxacin

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Ciprofloxacin is a broad-spectrum fluoroquinone antibiotic that is generally effective against both aerobic gram-positive and aerobic gram-negative bacteria. Bacterial organisms that have been shown to be targeted by ciprofloxacin are:
Ciprofloxacin is a broad-spectrum fluoroquinone antibiotic that is generally effective against both aerobic gram-positive and aerobic gram-negative bacteria. Bacterial organisms that have been shown to be targeted by ciprofloxacin are:
-
Aerobic Gram-Positive Bacteria (With Certain Strain Particularities):
+
''Aerobic Gram-Positive Bacteria (With Certain Strain Particularities)'':
 +
 
Enterococcus faecalis, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus saprophyticus,
Enterococcus faecalis, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus saprophyticus,
Streptococcus pneumoniae, etc.
Streptococcus pneumoniae, etc.
-
Aerobic Gram-Negative Bacteria (With Certain Strain Particularities):
+
''Aerobic Gram-Negative Bacteria (With Certain Strain Particularities)'':
 +
 
Campylobacter jejuni, Citrobacter freundii, Enterobacter cloacae, Escherichia coli, Haemophilus influenzae, etc.
Campylobacter jejuni, Citrobacter freundii, Enterobacter cloacae, Escherichia coli, Haemophilus influenzae, etc.

Revision as of 05:36, 6 March 2011

Please do NOT make changes to this Sandbox until after May 10, 2011. Sandbox 100 is reserved until then for use by John Ripollone - Messiah College, Grantham, PA (under the supervision of Dr. Hannah Tims).

Molecular Structure of Ciprofloxacin

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Ciprofloxacin

Page under construction - by: John Ripollone, Department of Biological Sciences (in conjunction with the Department of Chemistry and Biochemistry) - Messiah College, Grantham, PA 17027.

General Information

Ciprofloxacin is a broad-spectrum fluoroquinone antibiotic that is generally effective against both aerobic gram-positive and aerobic gram-negative bacteria. Bacterial organisms that have been shown to be targeted by ciprofloxacin are:

Aerobic Gram-Positive Bacteria (With Certain Strain Particularities):

Enterococcus faecalis, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus saprophyticus, Streptococcus pneumoniae, etc.

Aerobic Gram-Negative Bacteria (With Certain Strain Particularities):

Campylobacter jejuni, Citrobacter freundii, Enterobacter cloacae, Escherichia coli, Haemophilus influenzae, etc.

Structure

Ciprofloxacin is a 1-cyclopropyl-6-floro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid with molecular formula: C₁₇H₁₈FN₃O₃.


AcrB Multidrug Efflux Pump with Attached Ciprofloxacin

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Twinned Structure of S. Aureus Gyrase Complex with Attached Ciprofloxacin and DNA

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Proteopedia Page Contributors and Editors (what is this?)

John Ripollone, John E. Ripollone, Alexander Berchansky, David Canner

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