Methotrexate

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<Structure load='MTX' size='500' frame='true' align='right' caption='methotrexate structure' scene='Insert optional scene name here' />
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<Structure load='MTX' size='350' frame='true' align='right' caption='methotrexate structure' scene='Insert optional scene name here' />
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== Relevance ==
== Relevance ==
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<Structure load='2W3M' size='500' frame='true' align='right' caption='human DHFR with folate and NADPH' scene='Insert optional scene name here' />
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<Structure load='2w3m' size='350' frame='true' align='right' caption='human DHFR with folate and NADPH' scene='Insert optional scene name here' />

Revision as of 05:50, 10 March 2011

Please do NOT make changes to this Sandbox. Sandboxes 30-60 are reserved for use by Biochemistry 410 & 412 at Messiah College taught by Dr. Hannah Tims during Fall 2012 and Spring 2013.



Contents

Methotrexate

methotrexate structure

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INTRO

History

Relevance

human DHFR with folate and NADPH

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Structural Features

Mechanism of Action

HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND FOLATE 2w3m

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Pharmacokinetics

Image:thymidinesynthesis.jpg


[1].

Drug Treatment

Drug Synthesis

Protein Interactions

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greenlinks





References

  1. ↑ Voet, D., Voet, J. G., & Pratt, C. W. (2008). Fundamentals of biochemistry: life at the molecular level (3rd ed.). Hoboken, NJ: Wiley.

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Joel L. Sussman, Daniel Kreider, David Canner, OCA

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