Alendronate

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== '''Alendronate (Fosamax®)''' ==
== '''Alendronate (Fosamax®)''' ==
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Alendronate is commonly known for its use in treatment and prevention of osteoporosis in postmenopausal women and men, but is also used to treat Paget's disease (disease that results in deformed and enlarged bones).<ref>http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000018/</ref> Alendronate belongs to the class of nitrogen-containing bisphosphonates, which are inorganic pyrophosphate analogues.
Alendronate is commonly known for its use in treatment and prevention of osteoporosis in postmenopausal women and men, but is also used to treat Paget's disease (disease that results in deformed and enlarged bones).<ref>http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000018/</ref> Alendronate belongs to the class of nitrogen-containing bisphosphonates, which are inorganic pyrophosphate analogues.
== History of Bisphosphonates ==
== History of Bisphosphonates ==
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== Structure ==
== Structure ==
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== Target Protein ==
== Target Protein ==
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Revision as of 04:53, 11 March 2011

Please do NOT make changes to this Sandbox. Sandboxes 30-60 are reserved for use by Biochemistry 410 & 412 at Messiah College taught by Dr. Hannah Tims during Fall 2012 and Spring 2013.


Contents

Alendronate (Fosamax®)

Alendronate is commonly known for its use in treatment and prevention of osteoporosis in postmenopausal women and men, but is also used to treat Paget's disease (disease that results in deformed and enlarged bones).[1] Alendronate belongs to the class of nitrogen-containing bisphosphonates, which are inorganic pyrophosphate analogues.

History of Bisphosphonates

Structure

Target Protein

FPPS Asymmetric unit

Drag the structure with the mouse to rotate


Side affects of Drug






References



  1. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000018/

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Anne Goodling, David Canner, Justin Myles Kidd, OCA

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