Sandbox Reserved 339
From Proteopedia
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<Structure load='2ikh' size='500' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | <Structure load='2ikh' size='500' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | ||
[http://en.wikipedia.org/wiki/Aldose_reductase Wikipedia] | [http://en.wikipedia.org/wiki/Aldose_reductase Wikipedia] | ||
| - | == | + | ==Introduction== |
| + | Aldose reductase is an oxidoreductase/dehydrogenase enzyme.<ref name="wikipedia"> Wikipedia. Aldose Reductase. http://en.wikipedia.org/wiki/Aldose_reductase </ref> | ||
===Sub Title=== | ===Sub Title=== | ||
====Sub Sub Title==== | ====Sub Sub Title==== | ||
| - | Policosanol, a well-defined mixture of very long chain primary alcohols that is available as a nutraceutical product, has been reported to lower blood cholesterol levels.<ref name="placeholder"> PMID 21359855 </ref> | ||
In summary, this study provides the platform for further structure-guided design hypotheses of novel drug candidates with higher affinity and selectivity.<ref name="Steuber"> PMID 17368668 </ref> | In summary, this study provides the platform for further structure-guided design hypotheses of novel drug candidates with higher affinity and selectivity.<ref name="Steuber"> PMID 17368668 </ref> | ||
Revision as of 06:24, 11 March 2011
| This Sandbox is Reserved from January 10, 2010, through April 10, 2011 for use in BCMB 307-Proteins course taught by Andrea Gorrell at the University of Northern British Columbia, Prince George, BC, Canada. |
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Contents |
Aldose Reductase (2IKH)
|
Introduction
Aldose reductase is an oxidoreductase/dehydrogenase enzyme.[1]
Sub Title
Sub Sub Title
In summary, this study provides the platform for further structure-guided design hypotheses of novel drug candidates with higher affinity and selectivity.[2]
Title
References
- ↑ Wikipedia. Aldose Reductase. http://en.wikipedia.org/wiki/Aldose_reductase
- ↑ Steuber H, Heine A, Klebe G. Structural and thermodynamic study on aldose reductase: nitro-substituted inhibitors with strong enthalpic binding contribution. J Mol Biol. 2007 May 4;368(3):618-38. Epub 2006 Dec 15. PMID:17368668 doi:10.1016/j.jmb.2006.12.004
