3f6u

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==About this Structure==
==About this Structure==
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3F6U is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F6U OCA].
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[[3f6u]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F6U OCA].
==Reference==
==Reference==
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Thermodynamic linkage between the S1 site, the Na+ site, and the Ca2+ site in the protease domain of human activated protein C (APC). Sodium ion in the APC crystal structure is coordinated to four carbonyl groups from two separate loops., Schmidt AE, Padmanabhan K, Underwood MC, Bode W, Mather T, Bajaj SP, J Biol Chem. 2002 Aug 9;277(32):28987-95. Epub 2002 May 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12029084 12029084]
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<ref group="xtra">PMID:12029084</ref><ref group="xtra">PMID:9003757</ref><references group="xtra"/>
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The 2.8 A crystal structure of Gla-domainless activated protein C., Mather T, Oganessyan V, Hof P, Huber R, Foundling S, Esmon C, Bode W, EMBO J. 1996 Dec 16;15(24):6822-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9003757 9003757]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Bajaj, S P.]]
[[Category: Bajaj, S P.]]
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[[Category: Thrombophilia]]
[[Category: Thrombophilia]]
[[Category: Zymogen]]
[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Dec 5 09:51:33 2008''
 

Revision as of 12:36, 14 March 2011

Image:3f6u.png

Template:STRUCTURE 3f6u

Crystal structure of human Activated Protein C (APC) complexed with PPACK

Template:ABSTRACT PUBMED 12029084

About this Structure

3f6u is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Schmidt AE, Padmanabhan K, Underwood MC, Bode W, Mather T, Bajaj SP. Thermodynamic linkage between the S1 site, the Na+ site, and the Ca2+ site in the protease domain of human activated protein C (APC). Sodium ion in the APC crystal structure is coordinated to four carbonyl groups from two separate loops. J Biol Chem. 2002 Aug 9;277(32):28987-95. Epub 2002 May 23. PMID:12029084 doi:10.1074/jbc.M201892200
  • Mather T, Oganessyan V, Hof P, Huber R, Foundling S, Esmon C, Bode W. The 2.8 A crystal structure of Gla-domainless activated protein C. EMBO J. 1996 Dec 16;15(24):6822-31. PMID:9003757

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