3fl0
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3fl0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FL0 OCA]. | |
==Reference== | ==Reference== | ||
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[[Category: Quaternary structure flexibility]] | [[Category: Quaternary structure flexibility]] | ||
[[Category: Secreted]] | [[Category: Secreted]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 7 13:27:08 2009'' | ||
Revision as of 12:41, 14 March 2011
X-ray structure of the non covalent swapped form of the Q28L/K31C/S32C mutant of bovine pancreatic ribonuclease in complex with 2'-DEOXYCYTIDINE-2'-DEOXYGUANOSINE-3',5'-MONOPHOSPHATE
Template:ABSTRACT PUBMED 19280639
About this Structure
3fl0 is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
- Merlino A, Krauss IR, Perillo M, Mattia CA, Ercole C, Picone D, Vergara A, Sica F. Towards an antitumor form of bovine pancreatic ribonuclease: The crystal structure of three non-covalent dimeric mutants. Biopolymers. 2009 Mar 11. PMID:19280639 doi:10.1002/bip.21183
- Sica F, Di Fiore A, Merlino A, Mazzarella L. Structure and stability of the non-covalent swapped dimer of bovine seminal ribonuclease: an enzyme tailored to evade ribonuclease protein inhibitor. J Biol Chem. 2004 Aug 27;279(35):36753-60. Epub 2004 Jun 9. PMID:15192098 doi:http://dx.doi.org/10.1074/jbc.M405655200
- Merlino A, Ercole C, Picone D, Pizzo E, Mazzarella L, Sica F. The buried diversity of bovine seminal ribonuclease: shape and cytotoxicity of the swapped non-covalent form of the enzyme. J Mol Biol. 2008 Feb 15;376(2):427-37. Epub 2007 Nov 12. PMID:18164315 doi:http://dx.doi.org/10.1016/j.jmb.2007.11.008
- Di Donato A, Cafaro V, Romeo I, D'Alessio G. Hints on the evolutionary design of a dimeric RNase with special bioactions. Protein Sci. 1995 Aug;4(8):1470-7. PMID:8520472 doi:http://dx.doi.org/10.1002/pro.5560040804
Categories: Bos taurus | Pancreatic ribonuclease | Ercole, C. | Krauss, I Russo. | Mattia, C A. | Merlino, A. | Perillo, M. | Picone, D. | Sica, F. | Vergara, A. | 3d-domain swapping | Antitumor activity | Bovine seminal ribonuclease | Endonuclease | Glycation | Glycoprotein | Hydrolase | Non-covalent dimer | Nuclease | Protein mutations and evolution | Quaternary structure flexibility | Secreted
