This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3l8w
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | + | [[Image:3l8w.png|left|200px]] | |
| - | [[Image:3l8w. | + | |
<!-- | <!-- | ||
| Line 14: | Line 13: | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3l8w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspergillus_flavus Aspergillus flavus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L8W OCA]. | |
==Reference== | ==Reference== | ||
| Line 31: | Line 30: | ||
[[Category: Uric acid degradation]] | [[Category: Uric acid degradation]] | ||
[[Category: Xanthine]] | [[Category: Xanthine]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 2 08:38:47 2010'' | ||
Revision as of 12:42, 14 March 2011
Urate oxidase from aspergillus flavus complexed with xanthin
About this Structure
3l8w is a 1 chain structure with sequence from Aspergillus flavus. Full crystallographic information is available from OCA.
Reference
- Colloc'h N, el Hajji M, Bachet B, L'Hermite G, Schiltz M, Prange T, Castro B, Mornon JP. Crystal structure of the protein drug urate oxidase-inhibitor complex at 2.05 A resolution. Nat Struct Biol. 1997 Nov;4(11):947-52. PMID:9360612
- Gabison L, Chiadmi M, Colloc'h N, Castro B, El Hajji M, Prange T. Recapture of [S]-allantoin, the product of the two-step degradation of uric acid, by urate oxidase. FEBS Lett. 2006 Apr 3;580(8):2087-91. Epub 2006 Mar 10. PMID:16545381 doi:10.1016/j.febslet.2006.03.007
- Gabison L, Prange T, Colloc'h N, El Hajji M, Castro B, Chiadmi M. Structural analysis of urate oxidase in complex with its natural substrate inhibited by cyanide: mechanistic implications. BMC Struct Biol. 2008 Jul 20;8:32. PMID:18638417 doi:10.1186/1472-6807-8-32
- Colloc'h N, Gabison L, Monard G, Altarsha M, Chiadmi M, Marassio G, Sopkova-de Oliveira Santos J, El Hajji M, Castro B, Abraini JH, Prange T. Oxygen pressurized X-ray crystallography: probing the dioxygen binding site in cofactorless urate oxidase and implications for its catalytic mechanism. Biophys J. 2008 Sep;95(5):2415-22. Epub 2008 Mar 28. PMID:18375516 doi:10.1529/biophysj.107.122184
