1xf0

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Revision as of 12:45, 14 March 2011

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Template:STRUCTURE 1xf0

Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (AKR1C3) complexed with delta4-androstene-3,17-dione and NADP

Template:ABSTRACT PUBMED 15087468

About this Structure

1xf0 is a 1 chain structure with sequence from Homo sapiens. The August 2007 RCSB PDB Molecule of the Month feature on Anabolic Steroids by David S. Goodsell is 10.2210/rcsb_pdb/mom_2007_8. Full crystallographic information is available from OCA.

Reference

• Qiu W, Zhou M, Labrie F, Lin SX. Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues. Mol Endocrinol. 2004 Jul;18(7):1798-807. Epub 2004 Apr 15. PMID:15087468 doi:10.1210/me.2004-0032
• Zhou M, Qiu W, Chang HJ, Gangloff A, Lin SX. Purification, crystallization and preliminary X-ray diffraction results of human 17beta-hydroxysteroid dehydrogenase type 5. Acta Crystallogr D Biol Crystallogr. 2002 Jun;58(Pt 6 Pt 2):1048-50. Epub, 2002 May 29. PMID:12037313