2fix
From Proteopedia
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[[Image:2fix.png|left|200px]] | [[Image:2fix.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2fix]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIX OCA]. | |
==Reference== | ==Reference== | ||
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[[Category: Allosteric inhibitors human liver fbpase]] | [[Category: Allosteric inhibitors human liver fbpase]] | ||
[[Category: Benzoxazole]] | [[Category: Benzoxazole]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Intersubunit allosteric inhibitors of human liver fbpase]] | [[Category: Intersubunit allosteric inhibitors of human liver fbpase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:23:06 2009'' | ||
Revision as of 18:06, 14 March 2011
Structure of human liver FBPase complexed with potent benzoxazole allosteric inhibitiors
Template:ABSTRACT PUBMED 16446092
About this Structure
2fix is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Lai C, Gum RJ, Daly M, Fry EH, Hutchins C, Abad-Zapatero C, von Geldern TW. Benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1807-10. Epub 2006 Jan 30. PMID:16446092 doi:10.1016/j.bmcl.2006.01.014
- von Geldern TW, Lai C, Gum RJ, Daly M, Sun C, Fry EH, Abad-Zapatero C. Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1811-5. Epub 2006 Jan 25. PMID:16442285 doi:10.1016/j.bmcl.2006.01.015
