1yr2

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Template:STRUCTURE 1yr2

Structural and Mechanistic Analysis of Two Prolyl Endopeptidases: Role of Inter-Domain Dynamics in Catalysis and Specificity

Template:ABSTRACT PUBMED 15738423

About this Structure

1yr2 is a 1 chain structure with sequence from Novosphingobium capsulatum. Full crystallographic information is available from OCA.

Reference

  • Shan L, Mathews II, Khosla C. Structural and mechanistic analysis of two prolyl endopeptidases: role of interdomain dynamics in catalysis and specificity. Proc Natl Acad Sci U S A. 2005 Mar 8;102(10):3599-604. Epub 2005 Feb 28. PMID:15738423
  • Shan L, Marti T, Sollid LM, Gray GM, Khosla C. Comparative biochemical analysis of three bacterial prolyl endopeptidases: implications for coeliac sprue. Biochem J. 2004 Oct 15;383(Pt 2):311-8. PMID:15245330 doi:10.1042/BJ20040907
  • Polgar L. The prolyl oligopeptidase family. Cell Mol Life Sci. 2002 Feb;59(2):349-62. PMID:11915948

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