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2c0t

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{{Seed}}
 
[[Image:2c0t.png|left|200px]]
[[Image:2c0t.png|left|200px]]
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==About this Structure==
==About this Structure==
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2C0T is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C0T OCA].
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[[2c0t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C0T OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:16216497</ref><references group="xtra"/>
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<ref group="xtra">PMID:16216497</ref><ref group="xtra">PMID:15109663</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Transferase]]
[[Category: Transferase]]
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[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 10:07:40 2009''
 

Revision as of 18:42, 14 March 2011

Image:2c0t.png

Template:STRUCTURE 2c0t

SRC FAMILY KINASE HCK WITH BOUND INHIBITOR A-641359

Template:ABSTRACT PUBMED 16216497

About this Structure

2c0t is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Burchat A, Borhani DW, Calderwood DJ, Hirst GC, Li B, Stachlewitz RF. Discovery of A-770041, a src-family selective orally active lck inhibitor that prevents organ allograft rejection. Bioorg Med Chem Lett. 2006 Jan 1;16(1):118-22. Epub 2005 Oct 10. PMID:16216497 doi:10.1016/j.bmcl.2005.09.039
  • Borhani DW, Calderwood DJ, Friedman MM, Hirst GC, Li B, Leung AK, McRae B, Ratnofsky S, Ritter K, Waegell W. A-420983: a potent, orally active inhibitor of lck with efficacy in a model of transplant rejection. Bioorg Med Chem Lett. 2004 May 17;14(10):2613-6. PMID:15109663 doi:10.1016/j.bmcl.2004.02.101

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