3e6p
From Proteopedia
(Difference between revisions)
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[[Image:3e6p.png|left|200px]] | [[Image:3e6p.png|left|200px]] | ||
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{{ABSTRACT_PUBMED_18854941}} | {{ABSTRACT_PUBMED_18854941}} | ||
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- | ==Disease== | ||
- | Known disease associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]] | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[3e6p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E6P OCA]. | |
==Reference== | ==Reference== | ||
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[[Category: Thrombin]] | [[Category: Thrombin]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 15:58:07 2009'' |
Revision as of 18:51, 14 March 2011
Crystal structure of human meizothrombin desF1
Template:ABSTRACT PUBMED 18854941
About this Structure
3e6p is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Papaconstantinou ME, Gandhi PS, Chen Z, Bah A, Di Cera E. Na(+) binding to meizothrombin desF1. Cell Mol Life Sci. 2008 Nov;65(22):3688-97. PMID:18854941 doi:10.1007/s00018-008-8502-7
- Martin PD, Malkowski MG, Box J, Esmon CT, Edwards BF. New insights into the regulation of the blood clotting cascade derived from the X-ray crystal structure of bovine meizothrombin des F1 in complex with PPACK. Structure. 1997 Dec 15;5(12):1681-93. PMID:9438869
Categories: Homo sapiens | Thrombin | Bah, A. | Cera, E Di. | Chen, Z. | Gandhi, P. | Papaconstantinou, M E. | Acute phase | Allostery | Blood coagulation | Calcium | Cleavage on pair of basic residue | Disease mutation | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Kringle | Linkage | Meizothrombin | Na+ binding | Pharmaceutical | Polymorphism | Protease | Secreted | Serine protease | Zymogen