We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
2d1j
From Proteopedia
(Difference between revisions)
m (Protected "2d1j" [edit=sysop:move=sysop]) |
Revision as of 18:53, 14 March 2011
Factor Xa in complex with the inhibitor 2-[[4-[(5-chloroindol-2-yl)sulfonyl]piperazin-1-yl] carbonyl]thieno[3,2-b]pyridine n-oxide
Template:ABSTRACT PUBMED 15911309
About this Structure
2d1j is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Komoriya S, Haginoya N, Kobayashi S, Nagata T, Mochizuki A, Suzuki M, Yoshino T, Horino H, Nagahara T, Suzuki M, Isobe Y, Furugoori T. Design, synthesis, and biological activity of non-basic compounds as factor Xa inhibitors: SAR study of S1 and aryl binding sites. Bioorg Med Chem. 2005 Jun 2;13(12):3927-54. PMID:15911309 doi:10.1016/j.bmc.2005.04.006
- Haginoya N, Kobayashi S, Komoriya S, Yoshino T, Suzuki M, Shimada T, Watanabe K, Hirokawa Y, Furugori T, Nagahara T. Synthesis and conformational analysis of a non-amidine factor Xa inhibitor that incorporates 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine as S4 binding element. J Med Chem. 2004 Oct 7;47(21):5167-82. PMID:15456260 doi:10.1021/jm049884d
