1v16
From Proteopedia
(Difference between revisions)
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| - | {{Seed}} | ||
[[Image:1v16.png|left|200px]] | [[Image:1v16.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1v16]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V16 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:15166214</ref><references group="xtra"/> | + | <ref group="xtra">PMID:15166214</ref><ref group="xtra">PMID:12902323</ref><ref group="xtra">PMID:11069910</ref><ref group="xtra">PMID:10745006</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Chuang, D T.]] | [[Category: Chuang, D T.]] | ||
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[[Category: Branched-chain]] | [[Category: Branched-chain]] | ||
[[Category: Flavoprotein]] | [[Category: Flavoprotein]] | ||
| + | [[Category: Ketoacid dehydrogenase]] | ||
[[Category: Multi-enzyme complex]] | [[Category: Multi-enzyme complex]] | ||
[[Category: Oxidative decarboxylation maple syrup urine disease]] | [[Category: Oxidative decarboxylation maple syrup urine disease]] | ||
| - | [[Category: Oxidoreductase | + | [[Category: Oxidoreductase]] |
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
[[Category: Thiamine diphosphate]] | [[Category: Thiamine diphosphate]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:11:51 2009'' | ||
Revision as of 19:05, 14 March 2011
CROSSTALK BETWEEN COFACTOR BINDING AND THE PHOSPHORYLATION LOOP CONFORMATION IN THE BCKD MACHINE
Template:ABSTRACT PUBMED 15166214
About this Structure
1v16 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Li J, Wynn RM, Machius M, Chuang JL, Karthikeyan S, Tomchick DR, Chuang DT. Cross-talk between thiamin diphosphate binding and phosphorylation loop conformation in human branched-chain alpha-keto acid decarboxylase/dehydrogenase. J Biol Chem. 2004 Jul 30;279(31):32968-78. Epub 2004 May 27. PMID:15166214 doi:http://dx.doi.org/10.1074/jbc.M403611200
- Wynn RM, Machius M, Chuang JL, Li J, Tomchick DR, Chuang DT. Roles of His291-alpha and His146-beta' in the reductive acylation reaction catalyzed by human branched-chain alpha-ketoacid dehydrogenase: refined phosphorylation loop structure in the active site. J Biol Chem. 2003 Oct 31;278(44):43402-10. Epub 2003 Aug 5. PMID:12902323 doi:http://dx.doi.org/10.1074/jbc.M306204200
- Wynn RM, Ho R, Chuang JL, Chuang DT. Roles of active site and novel K+ ion-binding site residues in human mitochondrial branched-chain alpha-ketoacid decarboxylase/dehydrogenase. J Biol Chem. 2001 Feb 9;276(6):4168-74. Epub 2000 Nov 7. PMID:11069910 doi:10.1074/jbc.M008038200
- AEvarsson A, Chuang JL, Wynn RM, Turley S, Chuang DT, Hol WG. Crystal structure of human branched-chain alpha-ketoacid dehydrogenase and the molecular basis of multienzyme complex deficiency in maple syrup urine disease. Structure. 2000 Mar 15;8(3):277-91. PMID:10745006
Categories: Homo sapiens | Chuang, D T. | Chuang, J L. | Karthikeyan, S. | Li, J. | Machius, M. | Tomchick, D R. | Wynn, R M. | Acylation | Branched-chain | Flavoprotein | Ketoacid dehydrogenase | Multi-enzyme complex | Oxidative decarboxylation maple syrup urine disease | Oxidoreductase | Phosphorylation | Thiamine diphosphate
