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2kqg

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[[Image:2kqg.png|left|200px]]
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==About this Structure==
==About this Structure==
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2KQG is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2kj0 2kj0]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KQG OCA].
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[[2kqg]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2kj0 2kj0]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KQG OCA].
==Reference==
==Reference==
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[[Category: Oncogene]]
[[Category: Oncogene]]
[[Category: Promoter]]
[[Category: Promoter]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 25 09:23:02 2009''
 

Revision as of 19:08, 14 March 2011

Image:2kqg.png

Template:STRUCTURE 2kqg

A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics

Template:ABSTRACT PUBMED 19705869

About this Structure

2kqg is a 1 chain structure. This structure supersedes the now removed PDB entry 2kj0. Full experimental information is available from OCA.

Reference

  • Hsu ST, Varnai P, Bugaut A, Reszka AP, Neidle S, Balasubramanian S. A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics. J Am Chem Soc. 2009 Sep 23;131(37):13399-409. PMID:19705869 doi:10.1021/ja904007p
  • Fernando H, Reszka AP, Huppert J, Ladame S, Rankin S, Venkitaraman AR, Neidle S, Balasubramanian S. A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene. Biochemistry. 2006 Jun 27;45(25):7854-60. PMID:16784237 doi:10.1021/bi0601510

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