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1yz8
From Proteopedia
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[[Image:1yz8.png|left|200px]] | [[Image:1yz8.png|left|200px]] | ||
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{{ABSTRACT_PUBMED_15895993}} | {{ABSTRACT_PUBMED_15895993}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Iridogoniodysgenesis syndrome-2 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601542 601542]], Rieger syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601542 601542]], Ring dermoid of cornea OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601542 601542]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1yz8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YZ8 OCA]. | |
==Reference== | ==Reference== | ||
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[[Category: Rance, M.]] | [[Category: Rance, M.]] | ||
[[Category: Dna binding protein]] | [[Category: Dna binding protein]] | ||
| - | + | [[Category: Transcription/dna complex]] | |
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Revision as of 19:25, 14 March 2011
Solution structure of the k50 class homeodomain pitx2 bound to dna and implications for mutations that cause rieger syndrome
Template:ABSTRACT PUBMED 15895993
About this Structure
1yz8 is a 3 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
Reference
- Chaney BA, Clark-Baldwin K, Dave V, Ma J, Rance M. Solution structure of the K50 class homeodomain PITX2 bound to DNA and implications for mutations that cause Rieger syndrome. Biochemistry. 2005 May 24;44(20):7497-511. PMID:15895993 doi:10.1021/bi0473253
- Otting G, Qian YQ, Billeter M, Muller M, Affolter M, Gehring WJ, Wuthrich K. Protein--DNA contacts in the structure of a homeodomain--DNA complex determined by nuclear magnetic resonance spectroscopy in solution. EMBO J. 1990 Oct;9(10):3085-92. PMID:1976507
