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2e9r

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Revision as of 19:37, 14 March 2011

Image:2e9r.png

Template:STRUCTURE 2e9r

Foot-and-mouth disease virus RNA-dependent RNA polymerase in complex with a template-primer RNA and with ribavirin

Template:ABSTRACT PUBMED 17517631

About this Structure

2e9r is a 3 chain structure with sequence from Viruses. Full crystallographic information is available from OCA.

Reference

  • Ferrer-Orta C, Arias A, Perez-Luque R, Escarmis C, Domingo E, Verdaguer N. Sequential structures provide insights into the fidelity of RNA replication. Proc Natl Acad Sci U S A. 2007 May 29;104(22):9463-8. Epub 2007 May 21. PMID:17517631
  • Ferrer-Orta C, Arias A, Agudo R, Perez-Luque R, Escarmis C, Domingo E, Verdaguer N. The structure of a protein primer-polymerase complex in the initiation of genome replication. EMBO J. 2006 Feb 22;25(4):880-8. Epub 2006 Feb 2. PMID:16456546
  • Ferrer-Orta C, Arias A, Escarmis C, Verdaguer N. A comparison of viral RNA-dependent RNA polymerases. Curr Opin Struct Biol. 2006 Feb;16(1):27-34. Epub 2005 Dec 20. PMID:16364629 doi:10.1016/j.sbi.2005.12.002
  • Ferrer-Orta C, Arias A, Perez-Luque R, Escarmis C, Domingo E, Verdaguer N. Structure of foot-and-mouth disease virus RNA-dependent RNA polymerase and its complex with a template-primer RNA. J Biol Chem. 2004 Nov 5;279(45):47212-21. Epub 2004 Aug 3. PMID:15294895 doi:10.1074/jbc.M405465200
  • Arias A, Agudo R, Ferrer-Orta C, Perez-Luque R, Airaksinen A, Brocchi E, Domingo E, Verdaguer N, Escarmis C. Mutant viral polymerase in the transition of virus to error catastrophe identifies a critical site for RNA binding. J Mol Biol. 2005 Nov 11;353(5):1021-32. Epub 2005 Sep 26. PMID:16216271 doi:10.1016/j.jmb.2005.09.022

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