1wco

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{{Seed}}
 
[[Image:1wco.png|left|200px]]
[[Image:1wco.png|left|200px]]
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==About this Structure==
==About this Structure==
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1WCO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis] and [http://en.wikipedia.org/wiki/Monarthropalpus_flavus Monarthropalpus flavus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1uzt 1uzt]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WCO OCA].
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[[1wco]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis] and [http://en.wikipedia.org/wiki/Monarthropalpus_flavus Monarthropalpus flavus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1uzt 1uzt]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WCO OCA].
==Reference==
==Reference==
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The nisin-lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics., Hsu ST, Breukink E, Tischenko E, Lutters MA, de Kruijff B, Kaptein R, Bonvin AM, van Nuland NA, Nat Struct Mol Biol. 2004 Oct;11(10):963-7. Epub 2004 Sep 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15361862 15361862]
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<ref group="xtra">PMID:15361862</ref><ref group="xtra">PMID:12056898</ref><ref group="xtra">PMID:10600751</ref><ref group="xtra">PMID:12557191</ref><ref group="xtra">PMID:12580598</ref><references group="xtra"/>
[[Category: Lactococcus lactis]]
[[Category: Lactococcus lactis]]
[[Category: Monarthropalpus flavus]]
[[Category: Monarthropalpus flavus]]
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[[Category: Single protein]]
 
[[Category: Bonvin, A M.J J.]]
[[Category: Bonvin, A M.J J.]]
[[Category: Breukink, E.]]
[[Category: Breukink, E.]]
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[[Category: Pore formation]]
[[Category: Pore formation]]
[[Category: Pyrophosphate cage]]
[[Category: Pyrophosphate cage]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 19:19:04 2008''
 

Revision as of 19:39, 14 March 2011

Image:1wco.png

Template:STRUCTURE 1wco

THE SOLUTION STRUCTURE OF THE NISIN-LIPID II COMPLEX

Template:ABSTRACT PUBMED 15361862

About this Structure

1wco is a 2 chain structure with sequence from Lactococcus lactis and Monarthropalpus flavus. This structure supersedes the now removed PDB entry 1uzt. Full experimental information is available from OCA.

Reference

  • Hsu ST, Breukink E, Tischenko E, Lutters MA, de Kruijff B, Kaptein R, Bonvin AM, van Nuland NA. The nisin-lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics. Nat Struct Mol Biol. 2004 Oct;11(10):963-7. Epub 2004 Sep 12. PMID:15361862 doi:10.1038/nsmb830
  • Hsu ST, Breukink E, de Kruijff B, Kaptein R, Bonvin AM, van Nuland NA. Mapping the targeted membrane pore formation mechanism by solution NMR: the nisin Z and lipid II interaction in SDS micelles. Biochemistry. 2002 Jun 18;41(24):7670-6. PMID:12056898
  • Breukink E, Wiedemann I, van Kraaij C, Kuipers OP, Sahl H, de Kruijff B. Use of the cell wall precursor lipid II by a pore-forming peptide antibiotic. Science. 1999 Dec 17;286(5448):2361-4. PMID:10600751
  • Linge JP, Williams MA, Spronk CA, Bonvin AM, Nilges M. Refinement of protein structures in explicit solvent. Proteins. 2003 Feb 15;50(3):496-506. PMID:12557191 doi:10.1002/prot.10299
  • Dominguez C, Boelens R, Bonvin AM. HADDOCK: a protein-protein docking approach based on biochemical or biophysical information. J Am Chem Soc. 2003 Feb 19;125(7):1731-7. PMID:12580598 doi:10.1021/ja026939x

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