3c7p
From Proteopedia
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m (Protected "3c7p" [edit=sysop:move=sysop]) |
Revision as of 20:48, 14 March 2011
Crystal structure of human carbonic anhydrase II in complex with STX237
Template:ABSTRACT PUBMED 18723489
About this Structure
3c7p is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Woo LW, Fischer DS, Sharland CM, Trusselle M, Foster PA, Chander SK, Di Fiore A, Supuran CT, De Simone G, Purohit A, Reed MJ, Potter BV. Anticancer steroid sulfatase inhibitors: synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography. Mol Cancer Ther. 2008 Aug;7(8):2435-44. PMID:18723489 doi:7/8/2435
- Leese MP, Leblond B, Smith A, Newman SP, Di Fiore A, De Simone G, Supuran CT, Purohit A, Reed MJ, Potter BV. 2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity. J Med Chem. 2006 Dec 28;49(26):7683-96. PMID:17181151 doi:10.1021/jm060705x