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3pd9

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Revision as of 21:16, 14 March 2011

Template:STRUCTURE 3pd9

X-ray structure of the ligand-binding core of GluA2 in complex with (R)-5-HPCA at 2.1 A resolution

Template:ABSTRACT PUBMED 21067182

About this Structure

3pd9 is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Frydenvang K, Pickering DS, Greenwood JR, Krogsgaard-Larsen N, Brehm L, Nielsen B, Vogensen SB, Hald H, Kastrup JS, Krogsgaard-Larsen P, Clausen RP. Biostructural and Pharmacological Studies of Bicyclic Analogues of the 3-Isoxazolol Glutamate Receptor Agonist Ibotenic Acid. J Med Chem. 2010 Nov 10. PMID:21067182 doi:10.1021/jm101218a
  • Lunn ML, Hogner A, Stensbol TB, Gouaux E, Egebjerg J, Kastrup JS. Three-dimensional structure of the ligand-binding core of GluR2 in complex with the agonist (S)-ATPA: implications for receptor subunit selectivity. J Med Chem. 2003 Feb 27;46(5):872-5. PMID:12593667 doi:10.1021/jm021020+

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