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3q4c
From Proteopedia
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Revision as of 21:25, 14 March 2011
Crystal Structure of Wild Type BRAF kinase domain in complex with organometallic inhibitor CNS292
Template:ABSTRACT PUBMED 19371126
About this Structure
3q4c is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Xie P, Streu C, Qin J, Bregman H, Pagano N, Meggers E, Marmorstein R. The crystal structure of BRAF in complex with an organoruthenium inhibitor reveals a mechanism for inhibition of an active form of BRAF kinase. Biochemistry. 2009 Jun 16;48(23):5187-98. PMID:19371126 doi:10.1021/bi802067u
