3cf6
From Proteopedia
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m (Protected "3cf6" [edit=sysop:move=sysop]) |
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Structure of Epac2 in complex with cyclic-AMP and Rap
Template:ABSTRACT PUBMED 18660803
About this Structure
3cf6 is a 2 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.
Reference
- Rehmann H, Arias-Palomo E, Hadders MA, Schwede F, Llorca O, Bos JL. Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B. Nature. 2008 Sep 4;455(7209):124-7. Epub 2008 Jul 27. PMID:18660803 doi:http://dx.doi.org/10.1038/nature07187
- Rehmann H, Das J, Knipscheer P, Wittinghofer A, Bos JL. Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state. Nature. 2006 Feb 2;439(7076):625-8. PMID:16452984 doi:10.1038/nature04468
- Rehmann H, Prakash B, Wolf E, Rueppel A, de Rooij J, Bos JL, Wittinghofer A. Structure and regulation of the cAMP-binding domains of Epac2. Nat Struct Biol. 2003 Jan;10(1):26-32. PMID:12469113 doi:10.1038/nsb878
Categories: Homo sapiens | Mus musculus | Arias-Palomo, E. | Bos, J L. | Hadders, M A. | Llorca, O. | Rehmann, H. | Schwede, F. | Camp | Epac | G-protein | Gef | Gtp-binding | Gunanine nucleotide exchange factor | Nucleotide-binding | Rap | Rap1b | Rapgef4 | Signaling protein regulator/gtp-binding protein complex | Signaling protein/gtp-binding protein complex | Sp-camp