2vx1
From Proteopedia
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[[Image:2vx1.png|left|200px]] | [[Image:2vx1.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2vx1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX1 OCA]. | |
==Reference== | ==Reference== | ||
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[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
[[Category: Unphosphorylated]] | [[Category: Unphosphorylated]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 11 20:15:42 2009'' | ||
Revision as of 21:47, 14 March 2011
EPHB4 KINASE DOMAIN INHIBITOR COMPLEX
Template:ABSTRACT PUBMED 18851911
About this Structure
2vx1 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bardelle C, Coleman T, Cross D, Davenport S, Kettle JG, Ko EJ, Leach AG, Mortlock A, Read J, Roberts NJ, Robins P, Williams EJ. Inhibitors of the tyrosine kinase EphB4. Part 2: structure-based discovery and optimisation of 3,5-bis substituted anilinopyrimidines. Bioorg Med Chem Lett. 2008 Nov 1;18(21):5717-21. Epub 2008 Sep 27. PMID:18851911 doi:10.1016/j.bmcl.2008.09.087
- Bardelle C, Cross D, Davenport S, Kettle JG, Ko EJ, Leach AG, Mortlock A, Read J, Roberts NJ, Robins P, Williams EJ. Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines. Bioorg Med Chem Lett. 2008 May 1;18(9):2776-80. Epub 2008 Apr 10. PMID:18434142 doi:10.1016/j.bmcl.2008.04.015
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Barratt, D. | Brassington, C A. | Green, I. | Kettle, J G. | Leach, A G. | Mccall, E J. | Read, J. | Valentine, A L. | Atp-binding | Glycoprotein | Kinase | Membrane | Mutant | Nucleotide-binding | Phosphoprotein | Polymorphism | Receptor | Receptor tyrosine kinase | Transferase | Transmembrane | Tyrosine-protein kinase | Unphosphorylated
