2v4h

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Revision as of 21:50, 14 March 2011

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Template:STRUCTURE 2v4h

NEMO CC2-LZ DOMAIN - 1D5 DARPIN COMPLEX

Template:ABSTRACT PUBMED 19854204

About this Structure

2v4h is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

• Grubisha O, Kaminska M, Duquerroy S, Fontan E, Cordier F, Haouz A, Raynal B, Chiaravalli J, Delepierre M, Israel A, Veron M, Agou F. DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding. J Mol Biol. 2010 Jan 8;395(1):89-104. Epub 2009 Oct 23. PMID:19854204 doi:10.1016/j.jmb.2009.10.018
• Wyler E, Kaminska M, Coic YM, Baleux F, Veron M, Agou F. Inhibition of NF-kappaB activation with designed ankyrin-repeat proteins targeting the ubiquitin-binding/oligomerization domain of NEMO. Protein Sci. 2007 Sep;16(9):2013-22. PMID:17766391 doi:16/9/2013